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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Resveratrol
Research Papers that Mention the Interaction
“… MDA production … that RES (10(-10)mol/L to 10(-5)mol/L) could significantly increase the cell viability and decrease the LDH activity and that RES (…-like behavior of CUMS rats, as indicated by increased sucrose preference and decreased immobility in forced swimming test and tail suspension test.”
Antidepressant-like effect of resveratrol: Involvement of antioxidant effect and peripheral regulation on HPA axis“…)RES , rMnSOD, δ‐TOCO, and NAC, … reduced the intracellular levels of MDA induced by DAS or NIL; 2) RES, rMnSOD, and δ‐TOCO increased the intracellular ROS levels; 3) The increase … related to higher levels of oligonucleosomesi induced by DAS and NIL and that NAC significantly reduced this activity.”
“Simultaneously, resveratrol mitigated Cd-induced oxidative stress by reducing MDA and H2O2 production, alleviating GSH depletion and restoring the activity of antioxidant enzymes (T-SOD, Cu-Zn SOD, CAT, GST and GSH-Px).”
Ameliorative effects of resveratrol against cadmium-induced nephrotoxicity via modulating nuclear xenobiotic receptor response and PINK1/Parkin-mediated Mitophagy.“Results: Resveratrol significantly decreased mortality, neurological deficits, infarction volume and MDA levels and increased SOD activity.”
“The group concomitantly administered resveratrol was been found to be significantly decreased in MDA and NO levels and increased in GSH activity.”
“While LDH activity, capase-3 activity, Bax expression, intracellular calcium and MDA content were decreased by Res.”
“Treatment with resveratrol significantly reduced MDA , XO and NO production and increased glutathione levels when compared to the streptozotocin-induced diabetic-untreated group.”
“Subsequently, it was demonstrated treatment with PI3K/AKT pathway inhibitor (LY294002) or Wnt/…-1, DKK-1) could further enhance the anti-inflammatory and antioxidant effects of RSV by downregulating the expression of IL-… and TNFα, and the production of MDA , and increasing the activity of … in LPS-induced HGFs.”
Resveratrol prevents inflammation and oxidative stress response in LPS-induced human gingival fibroblasts by targeting the PI3K/AKT and Wnt/β-catenin signaling pathways“Moreover, addition of 90 mg/kg RES increased (P < 0.05) the activities of SOD, GSH-Px, and CAT and decreased (P < 0.05) the MDA levels in jejunal mucosa compared with the DIQ group.”
“Conclusion: Based on our findings, resveratrol has the potential to decrease diabetic vascular injury induced by lipid byproducts such as MDA.”
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