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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Lycopene
Research Papers that Mention the Interaction
“In addition, the H2 O2 -induced oxidative markers, including MDA , 8-OHdG, and protein carbonyls, were also downregulated by lycopene.”
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.“The activities of oxidative enzymes SOD and GSH-Px increased and MDA decreased in pancreatic tissue of rats after the intervention of lycopene.”
Effects of lycopene on metabolism of glycolipid in type 2 diabetic rats.“Additionally, we analyzed the oxidative stress levels in mice and found that LCP elevated SOD activity and suppressed MDA level in KA-induced seizures.”
“mRNA expression of SOD1 and SOD2 was significantly downregulated while MDA concentration was significantly increased in Ang II treated cells, which could be significantly reversed by cotreatment with Lyc in a dose dependent manner (all P < 0.01).”
“Additionally, LYC alleviated DON-induced oxidative stress by reducing ROS and MDA accumulation and enhancing the activity of antioxidant enzymes (CAT, T-SOD, T-AOC, and GSH-Px), which was linked with the activation of Nrf2 signaling and degradation of Keap1 expression.”
Lycopene Protects Intestinal Epithelium from Deoxynivalenol-Induced Oxidative Damage via Regulating Keap1/Nrf2 Signaling
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