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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Levocarnitine
Research Papers that Mention the Interaction
“The mice … 3% l-carnitine water for 12 weeks experienced a disturbance of the hepatic lipid metabolism, oxidative … and inflammation, which was evidenced by abnormal TC, LDL, RAHFR and MDA levels, unusual AST, ALT, ALP, SOD and GSP-Px activities, … increased IF-1, IF-6 and TNF-α expressions.”
Soluble soybean polysaccharides enhance the protective effects of genistein against hepatic injury in high l-carnitine-fed mice.“ l-Carnitine … serum MDA (2.46 ± 1.13 vs 2.16 ± 0.94 nmol/mL), total cholesterol (216.09 ± 34.54 vs 206.12 ± 39.74 mg/….69 vs 122.05 ± 32.76 mg/dL) levels compared with baseline (P < .05), whereas these parameters increased in the placebo group.”
“… L-carnitine also induced liver injury, which was proved by the increases in the serum AST and ALT activities, production of inflammatory liver cytokines (IL-…-6, TNF-α and TNF-β), lipid metabolism (TC, TG, HDL and LDL) disorder, and the decline in antioxidant ability (SOD, GSH-Px, MDA …).”
High L-carnitine ingestion impairs liver function by disordering gut bacteria composition in mice.“Administration of L-carnitine significantly reduced AA-induced elevations in AST, ALT, TSA and MDA concentrations and increased GSH levels at all sampling points.”
“Malonaldehyde MDA ) content was significantly decreased by CoQ10 and L-carnitine + CoQ10 supplementation.”
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