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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glutathione
Research Papers that Mention the Interaction
“In both models, CAT slightly inhibited CyA-dependent MDA formation and GLUT significantly inhibited MDA formation.”
“In both models, CCl4-dependent MDA formation was significantly inhibited by GLUT and showed no sensitivity to SOD or CAT.”
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes.“Serum GSH concentration negatively correlated with serum MDA (r=30.63, p<0.05) and NO(*) concentrations (r=0.72, p<0.05) in patients with advanced stage (III+IV).”
“In addition, Se decreased the contents of MDA and H2O2 and increased the activities of CAT, SOD, GST, GSH and GSH-Px, alleviating the imbalance of the redox system induced by Cd.”
Selenium Triggers Nrf2-AMPK Crosstalk to Alleviate Cadmium-Induced Autophagy in Rabbit Cerebrum.“This was associated with marked hepatic antioxidant effects [decrease MDA and NO levels, increase GSH and SOD activity].”
“DNA fragmentation and MDA concentrations were higher (P ≤ 0.05) in GSH 8 (12 ± 1.2% and 3.4 ± 0.09 nmol/ml).”
“PD significantly and dose-dependently reduces oxidative stress by lowering the content of oxidized glutathione (GSSG), reactive oxygen species (ROS), nitric oxide (NO) and malonaldehyde MDA ), while enhancing the hepatic activities of glutathione ( GSH ), glutathione peroxidase (GSH-Px) and the GSH/GSSG ratio.”
“Sioux significantly elevated serum total antioxidant … (TAC) and reduced glutathione GSH ) (0.33 mMol/l and 30.68 mg/dl, respectively), and significantly suppressed the markers of both lipid peroxidation (malondialdehyde, MDA ) and protein oxidation (protein carbonyl, PC) (14.25 µmol/ml and 3.18 nmol/mg protein, respectively).”
“substantially decreased (P<0.01) the activity level of testicular key enzymatic antioxidant biomarkers (superoxide dismutase, SOD; catalase, CAT and glutathione peroxidase, GPx), oxidative stress makers (blood hydroperoxide; testicular reduced glutathione, GSH and malondialdehyde, MDA ), and testicular mercury levels.”
“Furthermore, the activities of SOD and GSH in rat hippocampal tissue were found to have increased with a concomitant reduction in MDA levels, Bax expression, cytochrome c release, and the activity of caspase-9/3.”
“ GSH 5 mM also increased moderately MDA production and %DFI, possibly due to enhanced metabolic activity and reducing power.”
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