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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Berberine
Research Papers that Mention the Interaction
“Our results showed that the Ber pretreatment markedly increased CAT, SOD, and GSH-PX activities, decreased the levels of MDA , and improved the electrocardiogram and histopathological changes in the myocardium in DOX-treated rats (in vivo).”
Berberine Ameliorates Doxorubicin-Induced Cardiotoxicity via a SIRT1/p66Shc-Mediated Pathway“Pretreatment with BBR significantly reduced hepatic MDA and MPO levels, inhibited JNK phosphorylation and up-regulated the expression of nuclear Nrf-2 and its downstream gene Mn-SOD.”
“Treated with berberine for 4 weeks, elevated blood pressure and heightened levels of urine protein, blood urea nitrogen and serum creatinine in model rats were depressed significantly (P < 0.01), and elevated the activity of SOD, lowed the levels of MDA and GHb in blood serum (P < 0.01).”
“Furthermore, berberine treatment significantly blocked the increase of MDA , increased SOD and GSH-px levels in diabetic rats.”
“Pretreatment of myocytes with berberine resulted in reduction in LDH and MDA release (P < 0.01) in I/R groups, attenuation of apoptosis in ischemia and reperfusion groups (P < 0.01).”
“ Berberine significantly counteracted (P<0.05) the increase of TNF-α, IL-6, caspase-3 and BAX and counteracted the increase in plasma cTn-T and serum MDA.”
Berberine Protests the Heart from Ischemic Reperfusion Injury via Interference with Oxidative and Inflammatory Pathways“TNFα, IL6, and MDA increased in the RV, and PA, QS, and BBR significantly counterbalanced these increases.”
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