Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: 3,4-Methylenedioxyamphetamine and Berberine

Research Papers that Mention the Interaction

Our results showed that the Ber pretreatment markedly increased CAT, SOD, and GSH-PX activities, decreased the levels of MDA , and improved the electrocardiogram and histopathological changes in the myocardium in DOX-treated rats (in vivo).
Oxidative medicine and cellular longevity  •  2019  |  View Paper
Pretreatment with BBR significantly reduced hepatic MDA and MPO levels, inhibited JNK phosphorylation and up-regulated the expression of nuclear Nrf-2 and its downstream gene Mn-SOD.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2018  |  View Paper
Treated with berberine for 4 weeks, elevated blood pressure and heightened levels of urine protein, blood urea nitrogen and serum creatinine in model rats were depressed significantly (P < 0.01), and elevated the activity of SOD, lowed the levels of MDA and GHb in blood serum (P < 0.01).
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials  •  2011  |  View Paper
Furthermore, berberine treatment significantly blocked the increase of MDA , increased SOD and GSH-px levels in diabetic rats.
Journal of ethnopharmacology  •  2006  |  View Paper
Pretreatment of myocytes with berberine resulted in reduction in LDH and MDA release (P < 0.01) in I/R groups, attenuation of apoptosis in ischemia and reperfusion groups (P < 0.01).
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition  •  2003  |  View Paper
Berberine significantly counteracted (P<0.05) the increase of TNF-α, IL-6, caspase-3 and BAX and counteracted the increase in plasma cTn-T and serum MDA.
Medical archives  •  2021  |  View Paper
TNFα, IL6, and MDA increased in the RV, and PA, QS, and BBR significantly counterbalanced these increases.
Journal of cardiovascular pharmacology  •  2021  |  View Paper