supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Astaxanthin
Research Papers that Mention the Interaction
“The results showed that AST significantly decreased malonaldehyde ( MDA ) levels and increased antioxidase activity, in addition to demonstrating the ability to repair histopathological injuries to the liver, thereby attenuating oxidative stress.”
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.“ AST treatment could decrease the level of liver function indexes (ALT, GOT, ALP and TBil), reduce the concentration of MDA and ROS, and increase the activities of SOD, CAT and GPX in the liver.”
Astaxanthin from Haematococcus pluvialis ameliorates the chemotherapeutic drug (doxorubicin) induced liver injury through the Keap1/Nrf2/HO-1 pathway in mice.“Our findings indicate that high-dose administration of astaxanthin can blunt antioxidant enzyme activity and downregulate transcription of Nrf2 and Nrf2-dependent enzymes along with attenuating plasma and muscle MDA.”
“…,astaxanthin was shown to reduce the apoptosis of RGCs and … levels of oxidative stress markers, including superoxide anion, malondialdehyde ( MDA , a marker of lipid peroxidation), 8-hydroxy-2-deoxyguanosine (8-OHdG, indicator of oxidative DNA …) and MnSOD (manganese superoxide dismutase) activity in the retinal tissue of db/db mouse.”
“In addition, astaxanthin rich PR supplementation significantly increased serum GSH-Px and SOD activity (P<0.05), increased serum IgG content (P<0.05), and reduced MDA content (P<0.05) in laying hens.”
Astaxanthin supplementation enriches productive performance, physiological and immunological responses in laying hens
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback