Possible Interaction: 3,4-Methylenedioxyamphetamine and Antioxidants

“Discussion and conclusion: These findings suggest that MDA may be an additional clinical factor in assessing progression of HIV disease; however, necessary fortification of regimen with antioxidant may help reduce the high MDA concentration in the disease progression of the infection.”

“A significantly higher concentration of serum MDA ( p < 0.001) and low concentration of antioxidants (vitamin C) ( p < 0.001) are observed in patient than control group.”

“Both the antioxidants used in the present study markedly reduced the MDA levels.”

“A number of recognized antioxidants inhibited peroxide‐induced MDA formation.”

“ Antioxidant profiles were also highly significant with elevation in SOD, GPx, and CAT, but a reduction in MDA.”

“Both combined therapeutic regimens reduced MDA levels in tumor tissue, especially CM + TSPP + IR and increased the antioxidant defense and iNOS expression.”

“Furthermore MDA levels in the antioxidant groups were lower than control group (P < 0.05).”

“substantially decreased (P<0.01) the activity level of testicular key enzymatic antioxidant biomarkers (superoxide dismutase, SOD; catalase, CAT and glutathione peroxidase, GPx), oxidative stress makers (blood hydroperoxide; testicular reduced glutathione, GSH and malondialdehyde, MDA ), and testicular mercury levels.”

“Supplementation of antioxidants reduced the formation of MDA by 40% and COPs by 12% in fried eggs.”

“ Antioxidant treatment significantly reduced the GSH, nitrite/nitrate in ST and MDA levels.”