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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: 3-((6-Deoxymannopyranosyl)Oxy)-7-(Glucopyranosyloxy)-5-Hydroxy-2-(4-Methoxyphenyl)-8-(3-Methyl-2-Butenyl)-4H-1-Benzopyran-4-One and Calcium Supplement

Research Papers that Mention the Interaction

All these have demonstrated that icariin inhibited VSMCs calcification by down-regulating the ossification-related factors and lowering ALP activity and calcium content in VSMCs.
Icariin reversed the calcification of VSMCs induced by H_2O_2, inhibited ALP activity and calcium content in VSMCs, down-regulated the mRNA expression levels of OC, OPN, Runx2 and Col Ⅰa and Runx2 protein expression, and relatively up-regulated the expression of α-SMA.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  •  2021  |  View Paper
Alkaline phosphatase (ALP) was determined at 3, 6, 9, 12,15 d after intervention; calcified nodule was detected with alizarin …-I mRNA expression were observed with Real-time RT-PCR at 12, 24, 48, 72, 96 h. RESULT Genistein and icariin with the concentration of … the content of Ca, ….
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  •  2013  |  View Paper