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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Possible Interaction: 2-Amino-1-Methyl-6-Phenylimidazo(4,5-B)Pyridine and Conjugated Linoleic Acid
Research Papers that Mention the Interaction
“The addition of 1% CLA (w/w) in the diet starting 1 week prior to exposure to PhIP decreased PhIP-induced mutagenesis by 38% (P = 0.03).”
Conjugated linoleic acid inhibits mutagenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the prostate of Big Blue rats.“In a preliminary experiment, we found that CLA significantly reduced the induction of mutations by the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the distal colon in male rats.”
Effect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of rats.“Sex‐specific changes in mutation were observed following PhIP and CLA treatment.”
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