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“ PhIP increased the production of lipid peroxides and DAS decreased the PhIP-induced peroxidation by 47%.”
“We hypothesize that PhIP produces reactive oxygen species causing DNA strand breaks and that DAS will inhibit the formation of PhIP induced DNA strand breaks.”
“Administration of DAS , DPS and DPDS resulted in a significant increase of the activation of BaP, CP, N-PiP and PhIP mediated by S9 and microsomes while DADS treatment only increased the mutagenicity of PhIP.”